2021 SBML Draft |
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| Round 1 |
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| SMBL Team | Player | Pos | MLB Team |
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| Bangor | Dominic Smith | OF | NYM |
| Surrey | Corbin Carroll | OF | ARI |
| Terrace | Willi Castro | SS | DET |
| | Jared Walsh | 1B | LAA |
| Surrey | Nick Gonzales | SS/2B | PIT |
| Bangor | Teoscar Hernandez | OF | TOR |
| Kodiak | Alejandro Kirk | C | TOR |
| | Bryan Reynolds | OF | PIT |
| Rural Hall | Gunnar Henderson | SS | BAL |
| | Zac Veen | OF | COL |
| Tonganoxie | Ha-Seong Kim | SS/3B | SD |
| | Andres Gimenez | SS/2B | CLE |
| Western | Josh Jung | 3B | TEX |
| | Ryan Jeffers | C | MIN |
| Augusta | Wil Myers | OF | SD |
| | Ty France | IF | SEA |
| Eugene | Eric Hosmer | 1B | SD |
| | Mike Moustakas | 2B/3B | CIN |
| Lake Charles | Mitch Moreland | 1B | OAK |
| | Joey Votto | 1B | CIN |
| Carolina | Tyler Soderstrom | C | OAK |
| | Tommy Edman | 3B/OF | STL |
| Cohasset | Trent Grisham | OF | SD |
| | Jake Cronenworth | 2B | SD |
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| Round 2 |
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| SMBL Team | Player | Pos | MLB Team |
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| Surrey | Jordan Lawlar | SS | College |
| | Carter Kieboom | 3B | WAS |
| | Rowdy Tellez | 1B | TOR |
| | Danny Jansen | C | TOR |
| | Nick Senzel | OF | CIN |
| | Max Stassi | C | LAA |
| | Franmil Reyes | OF | CLE |
| | Jesus Aguilar | 1B | MIA |
| | Tommy La Stella | 2B | SF |
| Augusta | Isiah Kiner-Falefa | SS/3B | TEX |
| Carolina | Noelvi Marte | SS | SEA |
| Terrace | Jose Iglesias | SS | LAA |
| | Alex Dickerson | OF | SF |
| | Adam Duvall | OF | MIA |
| | Nico Hoerner | 2B | CHC |
| | Nate Lowe | 1B | TEX |
| Carolina | Jurickson Profar | 2B/OF | SD |
| Kodiak | Ramon Laureano | OF | OAK |
| | Pedro Severino | C | BAL |
| | Curt Casali | C | SF |
| | Ji-Man Choi | 1B | TB |
| | David Fletcher | 2B/SS/3B | LAA |
| | Jason Heyward | OF | CHC |
| | Dylan Moore | OF | SEA |
| Surrey | Josh Naylor | OF | CLE |
| | Nick Solak | 2B/OF | TEX |
| Bangor | Jorge Alfaro | C | MIA |
| | Kyle Farmer | 2B/SS | CIN |
| | Jon Berti | 2B/OF | MIA |
| | Heliot Ramos | OF | SF |
| | George Valera | OF | CLE |
| Rural Hall | Mike Brosseau | IF | TB |
| | Jeimer Candelario | 1B/3B | DET |
| | Victor Caratini | C | SD |
| | J.P. Crawford | SS | SEA |
| | Luis Torrens | C | SEA |
| | Cal Raleigh | C | SEA |
| | D'Angelo Ortiz | 3B | High School |
| Western | Heston Kjerstad | OF | BAL |
| | Joey Wendle | 2B/3B | TB |
| | Miguel Rojas | SS | MIA |
| | Yadier Molina | C | STL |
| Augusta | Danny Santana | 1B/OF | BOS |
| | Mauricio Dubon | OF | SF |
| | Michael Busch | 2B | LAD |
| Tonganoxie | Jose Trevino | C | TEX |
| | Cam Gallagher | C | KC |
| | Luis Urias | SS/3B | MIL |
| | Alexander Tejeda | SS | TEX |
| | Edwin Rios | 3B | LAD |
| | Garrett Mitchell | OF | MIL |
| | A.J. Pollock | OF | LAD |
| Augusta | Franchy Cordero | OF | BOS |
| | Bobby Bradley | 1B | CLE |
| | Mario Feliciano | C | MIL |
| | Ivan Herrera | C | STL |
| Western | To Be Determined | X | XXX |
| Augusta | Chance Sisco | C | BAL |
| Surrey | C.J. Cron | 1B | COL |
| Eugene | Patrick Bailey | C | SF |
| | Adrian Del Castillo | C | College |
| | Garrett Hampson | 2B/OF | COL |
| | Mitch Haniger | OF | SEA |
| | Scott Kingery | 2B/3B/OF | PHI |
| | Shohei Ohtani | DH | LAA |
| | Carlos Santana | 1B | KC |
| Lake Charles | Hudson Head | OF | PIT |
| | Cesar Hernandez | 2B | CLE |
| | Mickey Moniak | OF | PHI |
| | David Bote | 2B/3B | CHC |
| | Austin Slater | OF | SF |
| | Andrew McCutchen | OF | PHI |
| | Alex Avila | C | WAS |
| Terrace | Austin Hays | OF | BAL |
| Carolina | Donovan Solano | 2B | SF |
| | Randal Grichuk | OF | TOR |
| | Asdrubal Cabrera | 1B/3B | ARI |
| | Marwin Gonzalez | 2B/3B/OF | BOS |
| | Bo Naylor | C | CLE |
| | Robert Puason | SS | OAK |
| Cohasset | Jordan Walker | 3B | STL |
| | Garrett Cooper | 1B | MIA |
| | Brandon Nimmo | OF | NYM |
| | Jonathan India | 3B | CIN |
| | Brennen Davis | OF | CHC |
| | Cristian Hernandez | SS | CHC |
| | Austin Romine | C | CHC |
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| Round 3 |
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| SMBL Team | Player | Pos | MLB Team |
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| Surrey | Orelvis Martinez | SS | TOR |
| Terrace | Oswald Peraza | SS | NYY |
| Kodiak | Ed Howard | SS | CHC |
| Bangor | Rougned Odor | 2B | TEX |
| Rural Hall | Maximo Acosta | SS | TEX |
| Western | Charlie Tilson | OF | PIT |
| Tonganoxie | Austin Wells | C | NYY |
| Augusta | Bryce Ball | 1B | ATL |
| Eugene | Ronny Mauricio | SS | NYM |
| Lake Charles | Freddy Galvis | 2B/SS | BAL |
| Carolina | Roberto Perez | C | CLE |
| Cohasset | Kyle Higashioka | C | NYY |