2022 SBML Draft |
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| Round 1 |
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| SMBL Team | Player | Pos | MLB Team |
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| Lake Charles | Tyler O'Neill | OF | STL |
| | Druw Jones | OF | High School |
| Kodiak | Cedric Mullins | OF | BAL |
| | Jacob Berry | 3B/1B | College |
| Carolina | Marcelo Mayer | SS | BOS |
| | Anthony Volpe | SS | NYY |
| Surrey | Gabriel Moreno | C | TOR |
| | Jarred Kelenic | OF | SEA |
| Eugene | Henry Davis | C | PIT |
| | Brooks Lee | SS | College |
| Carolina | MJ Melendez | C | KC |
| Western | Nick Yorke | 2B | BOS |
| Augusta | Termarr Johnson | 2B | College |
| | Elijah Green | OF | College |
| Rural Hall | Nick Pratto | 1B | KC |
| | Nicky Lopez | SS | KC |
| Cohasset | Hunter Renfroe | OF | MIL |
| | Jesus Sanchez | OF | MIA |
| Tonganoxie | Jose Miranda | 2B | MIN |
| | Luis Arraez | 2B/3B | MIN |
| Bangor | Seiya Suzuki | OF | CHC |
| Tonganoxie | Brett Baty | 3B/OF | NYM |
| Carolina | Elly De La Cruz | SS | CIN |
| | Eugene Zunino | C | TB |
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| Round 2 |
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| SMBL Team | Player | Pos | MLB Team |
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| Lake Charles | Yadier Molina | C | STL |
| | Travis d'Arnaud | C | ATL |
| | Elias Diaz | C | COL |
| | Ben Rortvedt | C | NYY |
| | Shea Langeliers | C | OAK |
| | Justin Turner | 3B | LAD |
| | Alec Bohm | 3B | PHI |
| | Miguel Vargas | 3B | LAD |
| | Adam Frazier | 2B | SEA |
| | Josh Harrison | 2B | CHW |
| | Darin Ruf | 1B | SF |
| | Harrison Bader | OF | STL |
| | Alek Thomas | OF | ARI |
| Kodiak | Miguel Sano | 1B | MIN |
| Kodiak | Matt Chapman | 3B | TOR |
| Kodiak | Frank Schwindel | 1B | CHC |
| Kodiak | Bobby Bradley | 1B | CLE |
| Kodiak | Josh Rojas | 2B/SS/OF | ARI |
| Kodiak | Edmundo Sosa | SS | STL |
| Kodiak | Santiago Espinal | 3B | TOR |
| Eugene | Vidal Brujan | 2B+ | TB |
| | Brandon Crawford | SS | SF |
| | Tommy Edman | 2B/OF | STL |
| | Eric Haase | C | DET |
| | James McCann | C | NYM |
| | Jeff McNeil | 2B | NYM |
| | Jonathan Schoop | 1B | DET |
| Surrey | Garrett Cooper | OF | MIA |
| | Luis Garcia | 2B | WAS |
| | Andy Ibanez | U | TEX |
| | Rowdy Tellez | 1B | MIL |
| | Jacob Stallings | C | MIA |
| | Brandon Nimmo | OF | NYM |
| | Jeremy Pena | SS | HOU |
| Terrace | Matt Duffy | 3B | LAA |
| | Evan Longoria | 3B | SF |
| Western | Luis Matos | OF | SF |
| | Cristhian Vaquero | OF | WAS |
| Carolina | Tony Kemp | 2B/OF | OAK |
| | Patrick Wisdom | 3B | CHC |
| | Kyle Farmer | SS | CIN |
| | Terracey House | SS | WAS |
| Terrace | Antonio Gomez | C | NYY |
| | Anthony Garcia | 1B/OF | NYY |
| | Matt Vierling | OF | PHI |
| | Kevin Parada | C | College |
| | Miguel Bleis | OF | BOS |
| | Akil Baddoo | OF | DET |
| | Heston Kjerstad | OF | BAL |
| Rural Hall | Joey Lake Charles | 3B | MIA |
| | Brian Anderson | 3B | MIA |
| | Pedro Severino | C | MIL |
| | Christian Arroyo | 2B | BOS |
| | Garrett Hampson | 2B/OF | COL |
| | Tucker Barnhart | C | DET |
| | Harry Ford | C | SEA |
| Augusta | Jorge Alfaro | C | SD |
| | Donovan Solano | 2B | CIN |
| | Marcell Ozuna | OF | ATL |
| | Victor Robles | OF | WAS |
| | Adolis Garcia | OF | TEX |
| | Yandy Diaz | 3B/1B | TB |
| | Luis Torrens | C | SEA |
| Bangor | Avisail Garcia | OF | MIA |
| Tonganoxie | Tommy LaStella | 2B | SF |
| | Nick Fortes | C | MIA |
| | Curtis Mead | 3B | TB |
| | Josh Lowe | OF | TB |
| | Gio Urshela | 3B | MIN |
| | Mark Vientos | 3B | NYM |
| Cohasset | Connor Joe | OF+ | COL |
| | Yu Chang | 1B | CLE |
| | Jose Iglesias | SS | COL |
| | LaMonte Wade Jr. | OF | SF |
| | Tyler Naquin | OF | CIN |
| | Elehuris Montero | 1B | COL |
| | Jace Jung | 2B | College |
| Bangor | Trent Grisham | OF | SD |
| | Dominic Smith | OF | NYM |
| | Yoelqui Cespedes | OF | CHW |
| | Aledmys Diaz | U | HOU |
| | Leury Garcia | OF+ | CHW |
| | Yan Gomes | C | CHC |
| | Martin Maldonado | C | HOU |
| Carolina | Anthony Santander | OF | BAL |
| Western | Cesar Hernandez | 2B | WAS |
| | Ramon Urias | SS | BAL |
| | Chad Pinder | OF+ | OAK |
| | Kyle Seager | 3B | SEA |
| | Austin Hedges | C | CLE |
| | Roberto Perez | C | PIT |
| | JJ Bleday | OF | MIA |
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| Round 3 |
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| SMBL Team | Player | Pos | MLB Team |
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| Lake Charles | Michael Harris | OF | ATL |
| Kodiak | Tom Murphy | C | SEA |
| Eugene | Bryson Stott | SS | PHI |
| Surrey | Terrace Miller | 1B+ | TEX |
| Carolina | Kyle Higashioka | C | NYY |
| Terrace | Ezequiel Duran | IF | TEX |
| Rural Hall | Ricardo Cabrera | SS | CIN |
| Augusta | Andrew McCutchen | OF | MIL |
| Tonganoxie | Gavin Sheets | DH+ | CHW |
| Cohasset | Paul DeJong | SS | STL |
| Bangor | Pedro Leon | SS | HOU |
| Western | Asdrubal Cabrera | 3B | CIN |